Blar i NTNU Open på forfatter "Winther, Theo L."
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Correlation Between Digital and Manual Determinations of Ki-67/MIB-1 Proliferative Indices in Human Meningiomas
Pham, Duc-Tien; Skaland, Ivar; Winther, Theo L.; Salvesen, Øyvind; Torp, Sverre Helge (Peer reviewed; Journal article, 2019)Objective. Proliferative activity in tumor tissues is assessed as the percentage of Ki-67/MIB-1-positive cells, or the proliferative index (PI). The PI is routinely assessed manually. However, the subjectivity of manual ... -
DNA topoisomerase IIα and mitosin expression predict meningioma recurrence better than histopathological grade and MIB-1 after initial surgery
Winther, Theo L.; Torp, Sverre Helge (Journal article; Peer reviewed, 2017)Background: The 2016 WHO histopathological grade or conventional biomarker MIB-1 is insufficient for predicting meningioma recurrence after initial treatment and alternative strategies are required. In this study, we ... -
Prognostic value of ErbB2/HER2 in human meningiomas
Arnli, Magnus Bossum; Winther, Theo L.; Lydersen, Stian; Torp, Sverre Helge (Journal article; Peer reviewed, 2018)Introduction Among clinical challenges regarding human meningiomas is their propensity to recur even in cases with benign histology. Reliable biomarkers that can identify these cases are therefore highly desired. ErbB2/HER2 ... -
The anti-apoptotic protein survivin can improve the prognostication of meningioma patients
Winther, Theo L.; Torp, Sverre Helge (Journal article; Peer reviewed, 2017)Background The 2016 WHO histopathological grading includes a substantial within-variation in recurrence risk, and is thus insufficient to predict prognosis after initial surgery of patients suffering from meningiomas. ...